Polynucleotides
Polynucleotides (PN) are biocompatible, highly purified DNA fragments derived from natural sources, typically salmon or trout DNA. These long-chain molecules are rich in nucleotides — the building blocks of DNA — and are known for their ability to stimulate deep skin regeneration, healing, and hydration at a cellular level.
Unlike traditional fillers that volumize instantly, polynucleotides act as biostimulators — promoting the skin’s natural repair processes by activating fibroblasts and improving tissue quality over time.
KEY BENEFITS OF Polynucleotides
Polynucleotide therapy provides deep hydration and improved elasticity, helping the skin feel plumper, healthier, and more resilient. By stimulating the production of collagen and elastin, it strengthens the skin’s structure, restoring firmness and smoothing away fine lines, wrinkles, and visible signs of fatigue.
The treatment also enhances skin texture, tone, and natural glow, while repairing damage caused by sun exposure, stress, and environmental aggressors. Around the eyes, polynucleotides help reduce dark circles, puffiness, and crepey skin, brightening and refreshing this delicate area.
Because of their powerful regenerative properties, polynucleotides support healing in sensitive or acne-prone skin, calming inflammation and encouraging balanced skin function. Suitable for all skin types, including sensitive and aging skin, they provide a versatile solution for patients looking for natural, long-term skin rejuvenation.
You will experience
World-class DHA-certified medical artists
Bio-integrated skincare and injectables
Confidentiality that rivals concierge medicine
Results that are whisper-level flawless
FAQ's
What is Polynucleotide treatment?
Polynucleotide treatment is a non-surgical injectable therapy where a polynucleotide gel is delivered into targeted skin areas using a fine needle or cannula. Unlike fillers, it doesn’t add volume but instead rejuvenates the skin’s internal structure by stimulating cellular activity, collagen production, and microcirculation for long-term skin health.
How do polynucleotides work for skin rejuvenation?
Polynucleotides work through multiple mechanisms:
Cellular activation: They stimulate fibroblasts, the skin cells responsible for producing collagen and elastin.
Tissue repair: They reduce inflammation and enhance the skin’s natural healing processes.
Hydration: They attract and retain water, improving elasticity and suppleness.
Antioxidant effect: They help neutralize free radicals, protecting the skin from oxidative stress and premature aging.
How many sessions are needed?
An initial protocol of 3 sessions spaced 2–3 weeks apart is recommended for best results. Maintenance sessions are advised every 4–6 months, depending on age, skin condition, and goals. Visible improvements usually begin within 2–3 weeks, with progressive enhancement over 1–2 months.
What is the downtime after treatment?
Downtime is minimal. Patients may experience mild redness, swelling, or small bumps at the injection sites, which typically resolve within 24–72 hours. Makeup can usually be applied the next day, but it’s best to avoid heat, saunas, and strenuous exercise for 24–48 hours.
Who is the treatment best for?
Polynucleotide therapy is suitable for clients in their late 20s to 60s seeking natural anti-aging. It is ideal for those with dehydrated, dull, or tired-looking skin, early signs of aging, or loss of elasticity. It’s also a great option for individuals who prefer non-filler skin improvement and for those with sensitive or acne-prone skin.
Book an appointment
Leave us a message with your contact info and we will get back to you as soon as possible.